Abstract

<h3>Background</h3> The aim of this study was to present the prognostic factors for endometrial carcinoma. Microscopic type and grade, infiltration of uterine serosa, cervical invasion, and presence of lymph node and intraperitoneal metastases have been considered as prognostic factors. Mean nuclear volume, Ki67 and PTEN protein also provided prognostic information. <h3>Material and methods</h3> The tumor fragments were fixed in 10% formaldehyde and embedded in paraffin. The histological sections were stained with hematoxylin-eosin and by immunohistochemical methods (Ki67 and PTEN). <h3>Results</h3> Twenty-six endometrial carcinomas were evaluated histologically according to WHO and FIGO the recommendations. <h3>Conclusions</h3> The histologic parameters, mean nuclear volume, mitotic index, Ki67 and PTEN protein significantly correlated with survival and recurrence.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call