Abstract

Prognostic factors in endometrial cancer

Highlights

  • Endometrial cancer (EC) is the most common malignancy of the female genital tract

  • Univariate model revealed that the menopausal status, the FIGO stage, grade, histological type, myometrial invasion, ER, PR, peritoneal cytology, lymph node metastases, adjuvant therapy, and the method of operation ZHUH UHODWHG ZLWK WKH SURJQRVLV VLJQL¿FDQWO\ 7KH PXOWLYDULDWH DQDO\VLV &R[ SURSRUWLRQ KD]DUGV regression model showed that the ER (P=0.004), PR (P=0.000), myometrial invasion (P=0.006) DQG O\PSK QRGH PHWDVWDVHV 3 ZHUH UHODWHG ZLWK WKH SURJQRVLV VLJQL¿FDQWO\

  • Over the past few decades, several studies have demonstrated the prognostic importance of different parameters including lymph node status, histological type of carcinoma, histological grade and stage of disease, depth of myometrial invasion, lympho-vascular space involvement and cervical involvement

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Summary

Introduction

Endometrial cancer (EC) is the most common malignancy of the female genital tract It is the fourth most common gynecological cancer among women and the sixth worldwide cancer in Western countries. During the past two decades, there are improvements in treatment and its follow-up of endometrial car-cinoma patients, the importance of various prognostic factors has been extensively studied and published the prognostic parameters of endometrial cancer. These factors are important in tailoring proper adjuvant therapy consisting of modalities such as radiation, chemotherapy and hormonal therapy. Over the past few decades, several studies have demonstrated the prognostic importance of different parameters including lymph node status, histological type of carcinoma, histological grade and stage of disease, depth of myometrial invasion, lympho-vascular space involvement and cervical involvement

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