Prognostic and Diagnostic role of HE4 as a biomarker in ovarian cancer & comparison with CA125 in ovarian cancer patients with their menopausal status

Abstract

Aim: to evaluate a new tumour marker HE4, in comparison with CA 125 and the Risk of Ovarian cancer in pre and postmenopausal women with ovarian cancer.Method: The ovarian cancer female patients were recruited from OPD/IPD of Surgery and Oncology department of SMS Hospital, and evaluated serum human epididymis protein (HE4) and CA125 Patients were divided into two group’s premenopausal and postmenopausal women with ovarian cancer.Results: Serum HE4 and CA125 level significantly high in postmenopausal women as compared to premenopausal women of ovarian cancer. The result was significantly high. (p