Abstract
Objective To study the related prognostic factors influencing rectal neuroendocrine tumor prognosis. Methods We retrospectively reviewed tumor clinical and pathology material of 183 cases with rectal neuroendoerine in our hospital during recent 10 years and reclassified them according to the 2010 WHO pathology classification. Single factor and muhivariate analysis were performed to find related prognos- tic factors. Results Single factor analysis showed that tumor size （ 〈 1 cm, 1-2 cm, 〉2 cm, 98.77% vs 78. 57% vs 28.57%, X2 =71.4793, P =0.0001）, pathological grading （GI, G2, G3, 98.73% vs. 76. 19% vs 25. O0%,Xa =56. 5121, P =0. 0001） and the stage （stage Ⅰ , Ⅱ, Ⅲ, Ⅳ period, 99.40% vs 50. 00% vs 60.00% vs 16. 67% , X^2 = 105. 0383, P =0. 0001 ） among the three variables survival difference was statistically significant. Multivariate analysis （Cox regression） indicated that the tumor stage were inde-pendent factors affecting the prognosis, regression coefficient was 1. 277 （ B）, Wald value of 28. 145, Exp （B） a value of 3. 586, 95% CI： 2. 237-5. 747. Conclusion Tumor staging is an independent risk factor of survival, without considering other factors, different tumor size and pathologic grade also have different prog-nosis. Clinicians in making treatment plan should fully consider the above factors before choosing the appro-priate follow-up plan. Key words: Intestinal tumor; Rectum; Carcinoid tumor; Pathological; Prognosis
Published Version
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