Abstract

Abstract Introduction: The expanding use of multiwalled carbon nanotubes (MWCNTs) in various consumer and industrial products has raised concerns regarding the potential health risks following the ...

Highlights

  • The expanding use of multiwalled carbon nanotubes (MWCNTs) in various consumer and industrial products has raised concerns regarding the potential health risks following the inhalation of this nanomaterial

  • MWCNT dispersion in 1 mg/mL bovine serum albumin (BSA) resulted in a well-dispersed CNT suspension

  • Data obtained from in vivo and in vitro studies indicated that exposure to CNTs of specific physicochemical characteristics by inhalation can be associated with adverse effects such as pulmonary fibrosis similar to those induced by asbestos fibers.[8,43,44]

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Summary

Introduction

The expanding use of multiwalled carbon nanotubes (MWCNTs) in various consumer and industrial products has raised concerns regarding the potential health risks following the inhalation of this nanomaterial. Electrical conductivity, have heightened worldwide commercial interest.[3,4,5] the expanding use of CNTs has raised concerns, due to their potential biopersistence and high aspect ratio that are similar to specific types of micronsized asbestos fibers Such concerns were raised from several studies that indicated that exposure to CNTs may be associated with carcinogenic activity in the lung.[6,7,8,9] The potential risk is increased for long, thin fibers with high rigidity as they are able to reach deeper lung regions, where they can remain for extended periods due to impaired macrophage clearance.[10,11,12] recent in vivo studies reported increased lung injury, inflammation, fibrosis, and granuloma formation, following exposure to long multiwalled CNTs (MWCNTs) (10–30 lm).[13,14] Taken into consideration that human exposure to CNTs is highly possible within occupational, consumer, or environmental setting, there is heightened concern as to the pathogenic potential of CNTs.[4]

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