Abstract

Following four immobilized enzyme and microbial cell systems used for industrial production of optically active compounds are described.1Production of L-amino acids from acyl-DL-amino acids by immobilized aminoacylase.2Production of L-aspartic acid from ammonium fumarate by immobilized Escherichia coli cells having aspartase activity.3Production of L-malic acid from fumaric acid by immobilized Brevibacterium flavum cells having fumarase activity.4Production of L-alanine from ammonium fumarate by sequential use of immobilized E. coli cells having aspartase activity and immobilized Pseudomonas dacunhae cells having L-aspartate ß-decarboxylase activity.

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