Abstract
It is shown that osmium tetroxide, 2,2′-bipyridine can be applied as a probe of DNA structure in a bacterial cell. Using this probe we demonstrate (a) presence of structural distortions at the junctions between the right-handed B and left-handed Z DNA in a recombinant plasmid pRW751 and (b) unusual structure of the d(A-T) 16 insert in pAT32 plasmid in E. coli cells and in in vitro .
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