Abstract

It was shown that the complex of osmium tetroxide with N, N, N', N'-tetramethylethylendiamine can be applied as a probe of DNA structure in the cell. This probe site-specifically recognized structural distortions at the B-Z junctions in plasmids pRW751 and pPK1 (containing (dC-dG) n . segments) in E. coli cells.

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