Abstract

To analyze the cost variation of oral anti-diabetics of different generic drugs sold at Jan Avushadhi and jeevanadhara and Retail pharmacy available brand names of single compound and combination compounds to evaluate the difference in cost , percentage variation of cost. Cost of single and combination compound drugs manufactured by different companies, in the same strength, number and dosage form was obtained from Current Index of Medical Specialties” July-October 2014 and jan avushdhi,jeevandharaa drugs were compared upto February -2015. In Single compound drug usage, among sulfonylurea group of drugs, Glibenclamide (2 mg) shows maximum price variation of 1980%, while Glipizide (10mg) shows variation of 55.61%. In Biguanides & Thizolidinediones groups Of drugs Metformin (1000 mg) show Maximum price variation is 125.37%, Metformin (500 mg) leat variation is 30 % and Piglitazone (30mg) show Maxmum variation 3060.97% and least variation Pioglitazoe (15 mg) is 3275 respectively. . In α-glucosidases inhibitor group of drugs,Miglitol shows maximum price variation of 135.50 % and Minimum variation is 41.93 %. Meglitinides group of drugs. In this group, Rapaglinide (0.5 mg) shows Maximum price variation of 79.25 % and Minimum variation is 60 % respectively. Dipeptidyl peptidase IV inhibitors (e.g., Sitagliptin), group Sitagliptin (100 mg) shows Maximum price variation of 902.3 %. In combination therapiesGlibenclamide + Metformin (5 mg+ 500 mg) combination shows the maximum variation up to 2400 % and Glipizide + Metformin (2.5mg + 250mg) showed minimum price variation of 28.60% respectively. study has concluded that the cost variation increases when competition between the manufacturing companies and generic companies. cost which company providing less cost and whether these drugs are available janavushadhi or jeevandhara or generic pharmacy shops. So that we can minimize the cost burden on consumers.

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