Abstract
Preface Part I. General Background to Drug Usage in the Tropics: 1. Traditional medicine 2. The problems of availability and quality of modern drugs in the tropics Part II. Fundamental Pharmacodynamic Principles: 3. Measurement of drug response 4. Receptors and drug response Part III. Fundamental Principles in Drug Disposition: 5. Drug administration and factors affecting drug metabolism 6. Pharmacokinetic principles Part IV. Factors Affecting Drug Metabolism: 7. The influence of malnutrition and food-derived intoxicants 8. Genetic factors affecting drug action Part V. Selective Toxicity: 9. Antimicrobial drugs 10. Antiprotozoal drugs 11. Anthelmintics 12. Anticancer and antiviral drugs 13. Drug resistance 14. Strategies for the development of new drugs Part VI. Systematic Pharmacology: 15. Drug targets in the nervous system 16. Noradrenergic mechanisms 17. Cholinergic mechanisms 18. Anaesthesia 19. Pain and inflammation 20. Drugs acting on the central nervous system 21. Cardiovascular and renal systems 22. Haemopoietic system 23. Endocrine system 24. Local hormones (autocoids) Index.
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