Abstract

This review describes the design as well as advantages and disadvantages for current phenotypic (antibiogram and serotyping) and molecular techniques (plasmid analysis, arbitrarily primed PCR, 16S rRNA, pulse-field gel electrophoresis and multilocus sequence typing) for typing of commensal Neisseria spp. compared with pathogenic Neisseria species. Identical methods for typing Neisseria species should not be used in all situations, that is, for microepidemiological, macroepidemiological or evolutionary questions.

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