Abstract
A primordial odontogenic tumor (POT) is a rare benign mixed epithelial and mesenchymal odontogenic tumor that was included for the first time in the current World Health Organization (WHO) classification for head and neck tumors in 2017. Only seventeen cases of this tumor have been reported to the moment of writing this paper. We report a case of POT in a 13-year-old male patient presented with a painless enlargement of maxillary well-defined unilocular radiolucent lesion. Histologically, the tumor consisted mainly of loose fibrous connective tissue which resembles the dental papilla, and a single layer of columnar epithelial cells that covers the periphery of the tumor. Therefore, the histopathological diagnosis of POT was established. Immunohistochemical evaluation revealed a positive cytokeratin (CK) 19, and vimentin expression indicating a mixed tumor with a degree of differentiation corresponds approximately to that of the early bell stage of normal tissue from primary tooth germs.
Published Version
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