Abstract

Primary primitive neuroectodermal tumors (PNET) are rare and high-grade malignant tumors that mostly occur in children and young adults. PNET are divided into central-type PNET (cPNET) and peripheral-type PNET (pPNET) by the World Health Organization (WHO). pPNET majorly occur in soft tissues, skeleton, retroperitoneum and so on. pPNET of the cervix uteri is extremely rare. To date, few cases of pPNET of the cervix uteri have been reported in literature, and data on long term follow-up are not available. We focus on clinicopathologic profile, treatment, and clinical outcomes of patients with pPNET of cervix uteri by literatures review. Treatment strategies of pPNET of cervix uteri should be different from squamous carcinoma of the cervix (SCC) and adenocarcinoma of the cervix. Multimodality therapies including surgery, chemotherapy, radiotherapy and other treatment may prolong survival of patients of pPNET of cervix unteri. Key words: Neuroectodermal tumor, primitive; Cervix uteri neoplasms; Antineoplasic protocols

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