Primary Transitional Cell Carcinoma of Fallopian Tube in Postmenopausal Women: A Case Report and Review of Literature

Abstract

ABSTRACT Introduction Primary fallopian tube carcinoma is the least common gynecological malignancy encountered in practice. It accounts for about 1% of all cancers of a woman’s reproductive system, and it is more commonly seen in postmenopausal women. Transitional cell carcinoma (TCC) of the fallopian tube is a rare histological variant; only around 20 cases have been reported worldwide so far. The rate of preoperative diagnosis is in the range of 0 to 10%. Case report A 55-year-old P3L3 previous three normal vaginal delivery, postmenopausal for 6 years, type II diabetes mellitus patient presented with complaints of bleeding per vagina and excessive watery discharge per vagina for 6 months. Complete investigations and evaluation were done. Papanicolaou smear and endometrial aspiration were normal, and showed no evidence of malignancy. Taking age into consideration with duration of symptoms for 6 months, we went ahead with total abdominal hysterectomy with bilateral salpingo-oophorectomy. Intraoperatively, right hydrosalpinx was noted. Postoperatively, histopathology revealed right TCC of fallopian tube stage Ta1 Nx M0. Patient had wound infection postoperatively and was treated with IV antibiotics. Once infection settled, patient was taken up for diagnostic laparoscopy with omental biopsy and cystoscopy with bladder wall biopsy, which showed no evidence of malignancy. Conclusion It is more common for other cancers to spread to the fallopian tubes rather than for cancer to begin there. This diagnosis is rarely considered preoperatively and is usually first appreciated at the time of operation or by a pathologist. If detected early, fallopian tube cancer can often be successfully treated. How to cite this article Indumathi KPK, Bhuvana S, Vijayaraghavan J. Primary Transitional Cell Carcinoma of Fallopian Tube in Postmenopausal Women: A Case Report and Review of Literature. J South Asian Feder Menopause Soc 2017;5(1):58-61.