Abstract
Primary leiomyosarcoma in testis is an uncommon tumor with few cases reported. It generally develops after radiotherapy or long-term taking anabolic steroid medication. We report a 53-year-old male patient with primary testis leiomyosarcoma who presented with painless testicular enlargement without any known predisposing factors. Ultrasound revealed a large heterogeneous left testicular solid lesion. Alpha-fetoprotein (AFP) and beta-human chorionic gonadotrophin (beta-HCG) levels in serum were normal. Left radical orchidectomy following with histology assessment established a diagnosis of primary leiomyosarcoma of testis. No data of cancer metastasis was established. The patient didn’t receive any adjuvant therapy. There wasn’t any evidence of recurrence after 1 year follow-up. Leiomyosarcoma must be one of the differential diagnoses of seronegative tumors in testis. The motivation for this paper is the extreme infrequency of the situation and the differential diagnosis by all expansive inguinoscrotal tumors.
Highlights
IntroductionLeiomyosarcoma accounts for 5%–10% of sarcoma (1)
Primary leiomyosarcoma in testis is an uncommon tumor with few cases reported
Leiomyosarcoma in testis is an uncommon tumor which might happen after radiotherapy, chronic inflammation, or anabolic steroids use for long time
Summary
Leiomyosarcoma accounts for 5%–10% of sarcoma (1) It is a tumor originating from smooth muscle cells (2). General examination was insignificant except for a mass (about 4 cm in greatest diameter) in the left testis. The patient underwent ultrasound imaging, which showed a solid heterogeneous mass in the left testis. The patient was treated by inguinal high ligation radical orchiectomy due to suspicion of testicular malignancy. 462 Primary Testis Leiomyosarcoma malignant spindle cell tumor. The patient received no adjuvant therapy because no evidence of invasion to lymph node or other complications were observed. Follow up of the patient after 1 year shows no evidence of recurrence and he is asymptomatic until present
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