Abstract
Primary squamous cell carcinoma (SCC) of the thyroid gland is an extremely rare neoplasm with fewer than 55 reported cases. 1 The cancer, which resembles anaplastic carcinoma, tends to be advanced at presentation, with rapid progression and a poor prognosis. 2 Calcification is a common finding on thyroid imaging. Microcalcification is known to be associated with thyroid malignancy. 3 Eggshell or peripheral calcification was once thought to be an indicator that a tumor is benign, with few exceptions. Cases of papillary cell carcinoma, anaplastic carcinoma, and follicular cell carcinoma with this calcified pattern have been reported. 3 - 8 However, from review of the literature in English, no thyroid SCC with eggshell calcification has been reported. Here we report a case of primary SCC of the thyroid gland with eggshell calcification and its sonographic, computed tomographic (CT), and pathologic findings.
Published Version
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