Primary Squamous Cell Carcinoma of the Breast: A Rare Case Report and Management Decisions

Abstract

Background Squamous cells are normally not found inside the breast. Therefore, a primary squamous cell carcinoma of breast is an exceptional phenomenon and the management of this type of disease is still debated. The prognosis is poor, and hence there is a clinical trend to offer multimodal treatment options of surgery, chemotherapy and radiation therapy. Aim Clinical outcome assessment of patient with squamous cell carcinoma of the breast and management decisions. Materials and methods: we report case of primary squamous cell carcinoma of the breast T2N0Mx in a 78-years-old woman who underwent Modified Radical Mastectomy (MRM) plus adjuvant chemotherapy and hormonal therapy without radiation therapy and review literature for appropriate management decisions. Results With a follow up of 24 months, the patient is alive with no of local or distant recurrence. Conclusion Pure primary cell carcinoma of the breast is rare and aggressive disease, often treatment-refractory, our case show that the hormonal therapy after surgery and chemotherapy, allows to achieve a high local control. Multidisciplinary approach seems to be the optimal management for early stages in this rare disease.