Abstract
SummaryThe aim of the study was to evaluate the feasibility and most efficient way of offering middle-aged Swedish women a primary fracture screening program via a questionnaire. Two out of five invited women returned the FRAX questionnaire and those contacted directly by mail were most prone to respond.PurposeOsteoporosis and its associated fractures are increasing, and this study aims to explore ways to identify women at an increased risk of fracture using the FRAX® algorithm.MethodsThree thousand middle-aged women were invited and presented a questionnaire distributed by three different methods–by mail, at routine mammography, or internet-based.ResultsIn total, 1120 (37.3%) women responded to the questionnaire and agreed to participate. The response rates for the mail, mammography, and internet-based groups were 39.1%, 35.7%, and 25.2% respectively. Women in the mammography group weighed more, were slightly older than the other women, and also had a higher BMI than women from the mail and internet-based groups. No difference was observed between the groups regarding previous fracture, family history for fracture, current smoking, glucocorticoid use, and alcohol usage. The mammography group had a higher median (interquartile range) major osteoporotic FRAX® score (10.0% (7.8–17.0)) than the mail group (9.7% (7.1–15.0); p = 0.005) and the internet-based group (8.7% (6.7–14.0); p = 0.001).ConclusionsTwo out of five early postmenopausal women returned the questionnaire and women contacted directly by mail were more prone to respond. Out of the participants, 26.6% had a 10-year fracture risk score ≥ 15% according to the FRAX® algorithm.
Highlights
Osteoporosis and its subsequent high risk of fragility fractures are a huge and growing problem in the Western world
Arch Osteoporos (2019) 14: 51 evaluate the effect of primary screening using FRAX includes women between 65 and 80 years of age [6], and results recently published concluded that the systematic screening offered in the ROSE trial had no effect on fracture incidence in all women but a positive effect in women with moderate to high risk of fracture that chose to attend the offered DXA [7]
Women are invited to regular Swedish screening programs, i.e. cervical smear and mammography with participation rates of 80 to 82% that could be used as a possibility for further screening
Summary
Osteoporosis and its subsequent high risk of fragility fractures are a huge and growing problem in the Western world. Arch Osteoporos (2019) 14: 51 evaluate the effect of primary screening using FRAX includes women between 65 and 80 years of age [6], and results recently published concluded that the systematic screening offered in the ROSE trial had no effect on fracture incidence in all women but a positive effect in women with moderate to high risk of fracture that chose to attend the offered DXA [7]. In 2012, the Swedish National Board of Health and Welfare published guidelines regarding osteoporosis, recommending the use of FRAX® to calculate fracture risk when a clinical suspicion of osteoporosis is present [8]. The aim of the study was to evaluate the feasibility of offering women a primary fracture screening program via a wellknown standardised questionnaire and to investigate the most efficient way to offer the questionnaire
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