Abstract
Assessing the True Impact of Recurrent Fractures on Fracture Risk
Highlights
The major strategy to minimize the burden of osteoporotic fractures on society has been to identify and treat high-risk individuals before they fracture
This classification scheme clearly identifies those individuals with the highest risk of fracture, but because the greatest number of fractures occur in individuals with osteopenia or normal BMD, because of the much larger numbers of these individuals in the population, it is unable to prospectively identify many individuals who subsequently fracture.[5,6,7,8] As a result, a number of studies have attempted to identify risk factors in addition to BMD that would improve the ability to predict fractures in those with normal or osteopenic BMD
This study sought to quantify how many low-trauma fractures were first fractures and how many were repeat fractures in subjects randomly selected from the Canadian population for the Canadian Multicentre Osteoporosis Study (CaMOS)
Summary
The major strategy to minimize the burden of osteoporotic fractures on society has been to identify and treat high-risk individuals before they fracture. One of the strongest and most consistent risk factors across multiple studies in different populations is personal history of low-trauma fracture.[7,9,10] most cohort studies have excluded repeat fractures in the same individual from consideration during the study interval in the effort to estimate incident fractures. The study cohort at risk for first fracture included 2044 men with a mean follow-up of 5.8 yr and 4612 women with a mean follow-up of 6.0 yr.
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