Abstract

Primary peritoneal serous papillary carcinoma (PSPC) involving ovary and colon: Management and Treatment

Highlights

  • Primary peritoneal serous papillary carcinoma (PSPC) is a rare tumor of the peritoneum affecting mainly elderly and post-menopausal women

  • The pathogenesis of PSCP remains unclear, genealogical studies have led to the inclusion of peritoneal carcinoma in the hereditary breast ovarian cancer (HBOC) syndrome, which includes fallopian tube neoplasms

  • In 1993, the Gynecologic Oncology Group developed specific diagnostic criteria allowing the differentiation of PSCP from papillary serous ovarian carcinoma [4], which has similar histological aspect but different prognosis [5]

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Summary

Background

Primary peritoneal serous papillary carcinoma (PSPC) is a rare tumor of the peritoneum affecting mainly elderly and post-menopausal women. Ovarian serous tumors are generally discovered after spreading into the peritoneal surfaces; they are arbitrarily assigned to the ovary when involvement of this organ overtakes 5 mm [6]. This observation supports the hypothesis that papillary serous ovarian carcinoma originates from the epithelium. We present a case report of a 47-year-old woman who was admitted to our University-Hospital following diagnosis of pelvic mass She suffered from gastrointestinal symptomatology, observing alteration of bowel habit consisting in constipation alternated with diarrhea and associated with discomfort on the left iliac region. Final histological examination was not able to establish if the ovarian lesions were primary or secondary to a peritoneal extra ovarian serous carcinoma. After one year the patient is in good health and instrumental investigations (Ultrasounds, TC and NMR) are negative for recurrence

Discussion
Conclusion

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