Abstract
matched controls (GSP) were selected for each HIP case. Hospital course was then compared between the two groups, based on local/systemic complications of acute pancreatitis, management and length of stay. Statistics: Fischer's exact t-test was used and a two sided p-value was calculated; p-value of less than 0.05 was considered statistically significant. Results: There were 292 patients admitted during the study period. Etiologies were GSP (41.8%), alcoholic pancreatitis (23.3%), others (autoimmune, drugs, ERCP, idiopathic) (30.1%) and HIP (4.8%). There were 14 HIP cases (64% men)and 42 GSP controls (60% men). Mean age was 43.8 (range 24-64) and 44 (range 17-71) for cases and controls, respectively. Mean admission lipase levels were lower in HIP(638 mg/dl) than in GSP(2399 mg/dl). BISAP score on admission in all HIP cases was less than 2. As shown in the table, there was a significant difference between the two groups in the following variables: 2 or more abdominal CT scans, systemic complications (such as pleural effusions, ARDS, renal failure), transfer to the ICU (for renal failure,candidemia and respiratory distress) and use of TPN. There were no deaths in either group. Conclusions: Based on our data, HIP appears to follow a more aggressive course with greater resource utilization than GSP. Furthermore, a low BISAP score in HIP may not be predictive of in-hospital morbidity. These findings need to be confirmed in a prospective study with a larger sample size. Statistical comparison of various variables during the hospital course between cases (HIP) and controls (GSP)
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