PRIMARY NEUROENDOCRINE TUMORS

Abstract

Objective: To evaluate clinical presentation and surgical out come of primary neuroendocrine tumors of Kidney, U. bladderand Prostate gland. Design: A Retrospective study. Setting: Urology Department, SMBBMU Larkana. Period: 2001-2011. Patients andMethods: Series of 6 patients of primary neuroendocrine tumors of Kidney, U. bladder and Prostate gland were identified from 1890cases of urinary tract tumors. Two cases of renal carcinoid, two cases of small cell carcinoma of urinary bladder and two cases of smallcell carcinoma of prostate glands. Renal carcinoid tumors presenting with lumbar pain and microscopic haematuria and identified on theultrasound. Small cell carcinoma of urinary bladder presenting with dysuria, gross haematuria and on ultrasound while small cellcarcinoma of prostate gland presenting with irritatory and obstructive symptoms and confirmed on DRE. Results: 6 patients(5 male and1 female),Mean age of patients were 45years and range was 35-55 years. All patients treated primarily by definitive surgery like RadicalNephrectomy, TURBT and Pallitive TURP and all tumors confirmed on histopathological examination and referred to LINAR Larkana forproper managements. Conclusions: primary neuroendocrine tumors of Kidney, U.bladder and Prostate gland are rare tumors. Carcinoidtumors have good prognosis but small cell carcinoma have poor prognosis so require prompt treatment.