Abstract
Primary breast lymphoma is a rare tumor that presents commonly as a large mass with no specific mammographic appearance and can be confused with poorly differentiated carcinoma on frozen section. With appropriate treatment, this breast malignancy has a relatively good prognosis. We report a case of primary mammary non-Hodgkin lymphoma (NHL) in a 30-year-old young female presented with the complaint of painless lump in the right breast. Fine needle aspiration cytology (FNAC) suggested malignancy. Investigations ruled out metastasis, hence mastectomy was done. Immunochemistry of specimen revealed NHL of breast. Investigations to rule out any other site of lymphoma proved it to be primary NHL of breast with no metastasis. Anticancer drugs are main treatment rather than surgery so it is very important to accurately diagnose primary lymphoma of breast.
Highlights
In patients diagnosed with non-Hodgkin lymphoma (NHL), primary involvement of the breast is seen in 0.4–0.7% of the cases
We report a case that was diagnosed as malignant primary lymphoma of the breast and discuss diagnosis and management
On Sonography nodular type is seen as well marginated hypoechoic lobulated lesion (Figure 1B), which is similar to nodular lymphoma elsewhere in body where as diffuse type well defined hypoechoic area replaces normal breast parenchyma and Color Doppler imaging showed low resistance blood flow (Figure 1C)
Summary
Primary lymphoma is rare disorder of breast and constitutes less than 0.6% of all breast malignancies and 2.2% of extra nodal lymphomas [1,2]. We report a case that was diagnosed as malignant primary lymphoma of the breast and discuss diagnosis and management. 30 years old female presented to the Department of Radiotherapy, J.A. Group of Hospitals, Gwalior, India, with the complaint of painless lump in the right breast from two month, swelling over right scalp from one month, headache and dizziness from one month. Group of Hospitals, Gwalior, India, with the complaint of painless lump in the right breast from two month, swelling over right scalp from one month, headache and dizziness from one month She denied associated pain, fever, chills, or skin changes. Both axilla and left breast were normal. FNAC of breast and scalp lesion showed it was a high grade malignant Non Hodgkin’s B cell lymphoma. Immunohistochemistry showed high grade Non Hodgkin’s B cell lymphoma
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