Abstract
Primary intraosseous squamous cell carcinoma is a rare malignant tumour that exclusively arises within the jaws. Its diagnosis requires an appropriate clinical, imaging and histological correlation. The exclusion of primary oral mucosa lesions and metastatic disease is mandatory. We report an atypical imaging appearance of this uncommon entity, characterized by new bone formation and periosteal reaction that resemble sarcomatous or malignant odontogenic tumours. A comprehensive discussion on the embryological principles of primary intraosseous squamous cell carcinoma is also provided.
Highlights
Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare malignant tumour that arises within the jaws and derives from odontogenic epithelial remnants.[1,2,3,4] Owing to its rarity, clinical and radiological diagnostic criteria are not well established
Varied nomenclature has been used for this tumour since Loos first described it in 1913.2 Terminologies such as intra-alveolar epidermoid carcinoma or primary intra-alveolar epidermoid carcinoma have fallen in disuse and the most recent World Health Organization Classification of Tumours in 2005 used the term PIOSCC for this tumour.[2]
We report a PIOSCC with atypical imaging findings on both CT and MRI
Summary
Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare malignant tumour that arises within the jaws and derives from odontogenic epithelial remnants.[1,2,3,4] Owing to its rarity, clinical and radiological diagnostic criteria are not well established. BACKGROUND Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare malignant tumour that arises within the jaws and derives from odontogenic epithelial remnants.[1,2,3,4] Owing to its rarity, clinical and radiological diagnostic criteria are not well established. Clinical and imaging features are non-specific and the first impression of both clinicians and radiologists usually favours the diagnosis of alveolar or gingival SCC with bone invasion, or metastatic SCC.[5,6,7] We report a PIOSCC with atypical imaging findings on both CT and MRI.
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