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Abstract
Primary intraosseous squamous cell carcinoma (PIOSCC) developing from a Keratocystic odontogenic tumor (KCOT) is a rare malignant neoplasm of the jaws. The incidence of carcinomas arising in odontogenic cysts are less. This article presents a case of PIOSCC of the mandible developing from a KCOT in a 35-year-old male patient.
Highlights
Carcinoma arising from the wall of an odontogenic cyst is an extremely rare condition which is essentially limited to the jaws [1]
This article presents a case of a Primary intraosseous squamous cell carcinoma (PIOSCC) arising from a pre-existing Keratocystic odontogenic tumor (KCOT) in the posterior mandible
The clinical and radiographic features of carcinoma arising in an odontogenic cyst are non-specific, it may be difficult to distinguish between a simple odontogenic cyst and a malignant tumor
Summary
Carcinoma arising from the wall of an odontogenic cyst is an extremely rare condition which is essentially limited to the jaws [1]. Carcinomas can arise from long standing radicular cyst, residual cyst, dentigerous cyst, keratocystic odontogenic tumor, lateral periodontal cyst, and calcifying odontogenic cyst [2]. This article presents a case of a PIOSCC arising from a pre-existing KCOT in the posterior mandible. Epithelium showed discontinuity in the basement membrane with tumor cells invading into the connective tissue (Figure 4).
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