Abstract
Primary hyperparathyroidism is a result of increased and uncontrolled function of the parathyroid hormone caused by hyperfunction of one or more parathyroid glands. The cause of hyperfunction of the parathyroid glands could be adenoma, hyperplasia, and carcinoma. Primary Hyper parathyroidism is the most common cause of Hypercalcemia in outpatient population. The paper presents the case report of a 60years old female treated in our Hospital in March 2013. She presented in outpatient department with complaints of joints pain, Hypertension and renal failure for last 8years. After clinical, laboratory and radiological examination she was diagnosed as a case of PHPT due to a Giant Parathyroid Adenoma. After supportive, symptomatic and surgical treatment, the patient was back to normal daily activities without any signs of disease.
Highlights
Primary hyperparathyroidism occurs as a result of increased and uncontrolled secretion of parathyroid hormone because of hyperfunction of one or more parathyroid glands
In patients with primary hyperparathyroidism, calciuria has been reported, with an increased tendency to urolithiasis that can lead to Renal Failure and Hypertension, polyuria because of an osmotic diuresis which leads to dehydration and loss of weight [1,2,3]
Diuresis attributable to Hypercalcemia is accompanied by potassium loss; Hypercalcemia generally leads to hypokalemia
Summary
Primary hyperparathyroidism occurs as a result of increased and uncontrolled secretion of parathyroid hormone because of hyperfunction of one or more parathyroid glands. A 60 years old Female, Admitted in East surgical Ward Mayo Hospital Lahore in March 2013 with Suspicion of Parathyroid Adenoma Her detailed history showed that she had complaints of joints pain for the last 8years and was treated for arthritis in the form of painkillers and Calcium supplements but of no avail. She developed hypertension secondary to renal failure caused by nephrolithiasis She noticed epigastric pain, nausea, anorexia and weight loss. She was investigated for nephrolithiasis and was found Hypercalcemia in a specialized hospital and upon suspicion of Primary Hyperparathyroidism she was referred to us. Post Operatively PTH 51.10pg/ml, BUN 23, CREATININE 2.38, ALKALINE PHOSPHATASE 1081, SERUM CALCIUM 8.87
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