Abstract
BackgroundHepatic embryonal sarcoma (HES) is a rare but aggressive primary tumor of the liver occurring most frequently in childhood.Case presentationWe report a case of a 52 year old woman having previously undergone treatment for ovarian serous papillary carcinoma who subsequently presented with a large solitary mass in the liver. Initially this was presumed to be metastasis from the ovarian primary however, on further examination it was shown to be a primary hepatic embryonal sarcoma.ConclusionPrimary liver tumors should be considered in differential diagnoses in patients with ovarian cancer who subsequently present with liver tumors. This is particularly important when there is no direct evidence of recurrence of ovarian cancer.
Highlights
Hepatic embryonal sarcoma (HES) is a rare but aggressive primary tumor of the liver occurring most frequently in childhood.Case presentation: We report a case of a 52 year old woman having previously undergone treatment for ovarian serous papillary carcinoma who subsequently presented with a large solitary mass in the liver
Hepatic embryonal sarcoma (HES) is rare primary tumor of the liver usually occurring in childhood
We report a case of a woman who had previously undergone treatment for bilateral ovarian serous papillary carcinoma and subsequently presented with a large solitary mass in the liver which turned out to be a primary hepatic embryonal sarcoma
Summary
Hepatic embryonal sarcoma (HES) is rare primary tumor of the liver usually occurring in childhood. We report a case of a woman who had previously undergone treatment for bilateral ovarian serous papillary carcinoma and subsequently presented with a large solitary mass in the liver which turned out to be a primary hepatic embryonal sarcoma. A 52 year old woman presented with pain and a palpable mass in the right upper quadrant of the abdomen 18 months after completing treatment for ovarian carcinoma She had previously undergone bilateral salpingooophorectomy and en bloc subtotal colectomy for bilateral high-grade ovarian serous papillary carcinoma infiltrating the sigmoid colon. Immunohistochemical staining was positive for alpha1-antitrypsin but showed no other indicators of differentiation This contrasted with the serous papillary morphology of the previously resected ovarian tumor that showed no sarcomatoid areas and no rhabdoid differentiation. She received palliative care for gradual deterioration and died 6 months later
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