Primary Epithelioid Angiosarcoma of the Thyroid: Long-Term Survival Case Report and Literature Review

Abstract

Thyroid angiosarcoma is a rare neoplasm of debated clinical management. In addition, the epithelioid variant poses microscopic challenges due to its close resemblance to poorly differentiated carcinoma. Only 63 cases of thyroid angiosarcoma have been published in English literature. Due to its rarity, the limited clinical experience can make its management complex. We report a new case of primary thyroid angiosarcoma showing preponderant epithelioid features characterized by an exceptional long survival. We also provide a discussion on the role of radiotherapy in tumor treatment and a brief review of the pertinent literature.