Abstract
Primary alveolar rhabdomyosarcoma of breast in a 13 year old female with cardiopulmonary metastases and cyto-histological correlation: A case report
Highlights
Rhabdomyosarcoma is the commonest soft tissue sarcoma of childhood
We present a case report of a juvenile primary breast alveolar rhabdomyosarcoma
These findings and the histo-morphological pattern supported the diagnosis of Alveolar rhabdomyosarcoma, and excluded small cell carcinoma, lymphoma, Primitive neural ectodermal tumour (PNET) or epithelial neoplasm
Summary
Rhabdomyosarcoma is the commonest soft tissue sarcoma of childhood, accounting for 5% of malignant tumors in this age category [1, 2]. The patient was referred to our institution one year after the right breast lumpectomy She came with right breast tumour, associated nipple oedema and satellite areolar tumour nodules (Figure 1). A cytological diagnosis of malignant right breast neoplasm was made, differential of which included poorly differentiated carcinoma, rhabdomyosarcoma, Ewing’s’ sarcoma and lymphoma. A poorly differentiated or epitheloid leiomyosarcoma exhibit the same immunostaining profile but not the histomorphology of round small dark monotonous neoplastic cells separated by fibro vascular alveolar like septa seen in this case report. These findings and the histo-morphological pattern supported the diagnosis of Alveolar rhabdomyosarcoma, and excluded small cell carcinoma, lymphoma, Primitive neural ectodermal tumour (PNET) or epithelial neoplasm. A number of tumour nodules were seen on the heart (Figure 7) while both gross and histopathological findings were consistent with extensive tumour infiltration of the myocardium (Figure 5)
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
