Primary afferent and propriospinal fibers in the rat dorsal and dorsolateral funiculi.

Abstract

The purpose of this study is to determine the numbers of primary afferent and propriospinal fibers in the dorsal and dorsolateral funiculi of the rat. The reason for concentrating on these areas is that they contain large numbers of unmyelinated axons. Our data are axonal numbers from the S2 segment of spinal cord in animals that had unilateral dorsal rhizotomies or spinal cord isolations. The major conclusions are 1) that 23% of the primary afferent fibers in the dorsal funiculus are unmyelinated; 2) that there are approximately 12,500 unmyelinated primary afferent fibers in the dorsolateral funiculus, which is more than the number of primary afferent fibers in the dorsal funiculus and tract of Lissauer combined, and 3) that approximately 25% of the axons in the dorsal funiculus and 44% of the axons in the dorsolateral funiculus are propriospinal. These data modify and extend previous ideas of the organization of spinal white matter.