Abstract
Catechins are polyphenolic phytochemicals with many important physiological activities that play a multifaceted health care function in the human body, especially in the prevention of cardiovascular disease. In this paper, various experimental and clinical studies have revealed the role of catechins in the prevention and treatment of cardiovascular disorders, and we review the preventive effects of catechins on cardiovascular disease from the following aspects: Regulating lipid metabolism, regulating blood lipid metabolism, vascular endothelial protection, and reducing blood pressure.
Highlights
Catechins are polyphenolic phytochemicals that are widely distributed in food and medicinal plants, especially in all kinds of tea, and endow tea with various health benefits [1,2,3]
Of theBecause special of structure, catechins are catechins endowed are endowed with strong antioxidant unique on the prevention of cardiovascular with strong antioxidant activity andactivity uniqueand effects on effects the prevention of cardiovascular disease disease gallate (ECG), and epigallocatechin gallate (EGCG) [25]
Catechins could regulate the RNA and protein expression of fatty acid metabolism in the liver affect of metabolic can improve the improve oxidationthe of fatty acids enzymes intothe liverthe to activity affect the activity ofenzymes, metabolicwhich enzymes, which can oxidation and the acids inhibition acid synthesis, so assynthesis, to reduce the lipid levels inthe thelipid blood and in liver, well of fatty and of thefatty inhibition of fatty acid so as to reduce levels theas blood as decrease body fat deposition, reducing early onset of cardiovascular disease in children and liver, as well as decrease body fat deposition, reducing early onset of cardiovascular disease
Summary
Catechins are polyphenolic phytochemicals that are widely distributed in food and medicinal plants, especially in all kinds of tea, and endow tea with various health benefits [1,2,3]. A growing number of studies have linked intake of catechins-rich foods with the prevention of human chronic diseases, and laboratory studies have demonstrated the potential preventive activity of catechins in laboratory models of cardiovascular disease [4]. Irregular life and unhealthy diets cause more people to suffer from cardiovascular diseases, such as obesity, fat deposits, and so on [7]. Caffeine, and many kinds of beneficial active materials, which play an important role in human health [8,9,10]. Catechins have a significant effect on the prevention of cardiovascular disease [11,12,13]. This paper has reviewed the preventive effects of catechins on cardiovascular disease, which were published in the past few decades
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