Abstract

A nulliparous Rh-negative woman received approximately 500 ml. of Rh-positive blood following acute blood loss associated with an incomplete abortion. Twenty vials of Rh-immune globulin were administered to her in divided doses within 72 hours after transfusion. This was followed by the development of a passive anti-Rh titer of 1:16 and the disappearance of the transfused Rh-positive cells from her circulation over a 12 day period. No adverse reaction was experienced by the patient and an eight-month follow-up indicates no evidence of active Rh immunization.

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