Abstract
Prevention of major depression in at-risk adolescents: a pilot randomised trial of a screen-and-intervene program
Highlights
Given the findings above relating to the low recruitment rates for the study, it is clear that approaching parents through IAPT services and GP practices in this way is not a feasible method of identifying eligible parents and young people for a depression prevention study such as this
Considering the smaller proportion of young people scoring in the High-risk group than expected, it may be useful for future studies to consider the effectiveness of the Mood and Feelings Questionnaire (MFQ) as a screening measure of depression in young people, and whether such a measure is needed given all young people could be considered High-risk by virtue of having a parent with a history of depression
Given the low participation rate so far in the Cognitive Behavioural Therapy (CBT) groups for 14-17 year-olds, a different approach may be needed to engage this group of young people
Summary
Depression is common among adolescents, and associated with academic and social impairment, family burden and high rates of attempted and completed suicide. Many cases of adolescent-onset depression continue into adulthood, and each episode of depression raises the risk of a subsequent episode, with repeated episodes being increasingly hard to treat. In this context, recent efforts have been made to prevent the onset of depression in adolescence; no study of targeted depression prevention programmes had been completed in the UK
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