Prevention of ketosis in cows: the role and effectiveness of Кеххtone

Abstract

Ketosis is a common metabolic disease in dairy cattle that is often diagnosed in the late stages of pregnancy or early stages of lactation, especially in high-yield cows. To counteract this disease, we used the drug Kexxtone, which protects for 95 days, starting from 3–4 weeks before the planned calving. The study showed that the administration of this drug led to a significant decrease in the level of ketone bodies in the blood of cows on the third and ninth day after calving. Notably, on the third day after calving, the content of ketone bodies in the blood of animals treated with the drug during the second lactation was significantly lower than in the control group of cows by 1.38 times (Р < 0.05), on the ninth day of research, this indicator in cows of this group significantly decreased by 2.48 times and amounted to 0.81 ± 0.05 mmol/L (Р < 0.01), and in the control group – 2.01 ± 0.31 mmol/L. It was also found that the insemination index was almost the same in cows during the second lactation. Still, a significant decrease in this indicator was noted in the third and fourth lactation of cows when using the drug Kexxtone. Thus, during the third lactation in experimental cows, this index was 1.6 ± 0.18 (Р < 0.01), and in the control group – 2.13 ± 0.35. In cows of the experimental groups, a higher average daily milk yield was observed compared to animals that were not given the drug. In some cows during the fourth lactation, which was not treated with Kexxtone, high levels of ketone bodies were detected in the blood, which may indicate the need for health monitoring and additional measures to prevent ketosis. In addition, a high average daily milk yield was found in cows from the experimental groups, possibly due to the drug Kexxtone's positive effect on the animal body's physiological processes and increased productivity of dairy cattle. These results indicate the potential benefits of using Kexxtone to ensure the health and productivity of cows at different stages of their life. These results allow us to recommend the use of the drug to prevent the occurrence of ketosis and increase cow yield. Additional research may be helpful for a deeper understanding of the mechanisms of the drug's action and its effect on the body and productivity of cows.