Abstract
ObjectiveThe objective of this study was to evaluate the trend and prevalence of prediabetes and diabetes among high-risk adults in Shanghai from 2002 to 2012.MethodsFrom 2002 to 2012, 10043 subjects with known risk factors for diabetes participated in the diabetes-screening project at the Shanghai Sixth People’s Hospital of Shanghai Jiao Tong University. All participants were asked to complete a nurse-administered standard questionnaire concerning age, sex, smoking status, and personal and family histories of diabetes, cardiovascular disease, stroke, hypertension and other diseases. The participants’ body mass index scores, blood pressures and blood glucose levels at 0, 30, 60, 120 and 180 min were measured in response to a 75 g oral glucose tolerance test.ResultsThe overall prevalence of diabetes increased from 27.93% to 34.78% between 2002 and 2012 in high-risk subjects. The study also showed that the prevalence increased much faster in male compared to female subjects. Specifically, an increased rate was seen in middle-aged men, with no change observed in middle-aged females over the eleven-year period.ConclusionThis study showed that sex, age, parental diabetic history, and being overweight were associated with an increased risk for diabetes in high-risk people. Therefore, as prediabetes and diabetes are highly prevalent in people with multiple diabetes risk factors in Shanghai, screening programs targeting these individuals may be beneficial.
Highlights
Diabetes is becoming a global public health threat, largely due to an increase in type 2 diabetes
In an effort to describe the prevalence and trends of prediabetes and diabetes among high-risk Chinese adults over the past decade, this study examined oral glucose tolerance test (OGTT) results from Chinese subjects identified as high-risk through an outpatient diabetes screening project (Shanghai High-risk Diabetic screen project, SHiDS)
While there were no differences in the associations of Body mass index (BMI) and age between males and females (Figure 1), there were some sex differences observed
Summary
Diabetes is becoming a global public health threat, largely due to an increase in type 2 diabetes. The prevalence among adults is expected to rise from 371 million in 2012 to 552 million by the year 2030 [1,2]. With the rapid economic growth, increase in life expectancy, and a shift towards a higher calorie diet and sedentary lifestyle, the prevalence of diabetes in China has increased over the past few decades from 2.5% in 1994 to 9.7% in 2008 [3,4]. China has the largest number of diabetics in the world, with estimates of 92.4 million diabetic adults and an additional 148.2 million adults with prediabetes in 2007–2008 [4]. It should be noted that the American Diabetes Association recommends screening adults with prediabetes every year, and those at risk for diabetes every three years [5]. To date, the prevalence and trends of the diabetes epidemic in high-risk subjects has not been well examined
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