Abstract
Thyroid issues have long been debated as a possible cause of gall stone disease. The link between hypothyroidism and gallstone disease could be explained in a variety of ways. The main objective of this study is to determine the prevalence of hypothyroidism in gallstone patients and to rule out hypothyroidism as a probable cause of gallstone formation. A prospective study was conducted in surgical wards of Department of surgery sree balaji medical college from 2016 to 2017. All patients were evaluated using a comprehensive clinical history and examination, as well as suitable investigations such as abdominal USG, thyroid function tests, and lipid profiles. Out of 22 patients 19 patients (86.4%) had normal TSH, 2 patients (9.1%) had increased TSH, 1 patient (4.5%) had decreased TSH. Raised TSH was more in the AGE Group of 61- 75 years, which is comparable to other studies. Out of 22 patients, (100%) had normal T3 levels. 19 patients (86.4%) had normal T4 levels and Ultrasound examination of neck, 2 patients (9.1%) had decreased T4 level and 1 patient (4.5%) had increased T4 levels and 3 patients (13.6%) had abnormal Ultrasound Neck findings. Hence In this Study Cholelithiasis is most commonly seen in Females of age group of 41-60 years and prevalence of raised TSH level in cholelithiasis patient was 9% and most were found in the age group of 61-80 years.
Highlights
Gallstones are the most prevalent biliary pathology and are classified as cholesterol, pigment, or mixed stones
Hypothyroidism in the subclinical stage is more common than hypothyroidism in the acute stage
Females are more likely than men to suffer from hypothyroidism
Summary
Gallstones are the most prevalent biliary pathology and are classified as cholesterol, pigment (black, brown), or mixed stones. Cholesterol or mixed stones are composed of 51–99% cholesterol, as well as calcium salts, bile acids, bile pigment, and phospholipids [1]. There have been few previous investigations on the prevalence of thyroid problems in healthy people. According to a recent study from the United Kingdom, thyroid issues affect 3.6 % of healthy people. There has been debate for a decade about whether thyroid issues might cause gallstone disease [5,6,7]. There are various plausible explanations for a probable association between hypothyroidism and gallstone disease; these possibilities include the established link between thyroid failure and lipid metabolic abnormalities, which may lead to a change in bile composition
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