Abstract
The incidence of vaccine preventable diseases has increased in the adult Japanese population. The purpose of this study was to determine the need for vaccinations in students of co-medical field. Status of the students attending to International University of health and welfare, Japan were surveyed in 2008 to 2011 academic year for vaccination and past medical history by self-administered questionnaire and the serum antibody prevalence for enrollment concerning measles, rubella, varicella and mumps. Majority of the students in all years had immunity for measles, rubella and varicella but not for mumps by EIA assy. Although positive rates of measles antibody had risen since 2009, which of rubella was extremely low in the year of 2011. Serum antibody titers of rubella were lower than those of measles in all years. Freshman of 2008 showed highest antibody titers against measles and rubella. These results suggest that the forth stage of measles and rubella mixed regular vaccination targeted since 2008 in Japan was effective. Also determined what should be done the encouraging vaccination based on specific past medical history, vaccination histories (including dates and times) about encouraging vaccination, appropriate for the individual.
Highlights
Anahtar Kelimeler: Kızamık, kızamıkçık, suçiçeği, kabakulak, aşı measles, mumps, rubella, and varicella (MMRV) are vaccine-preventable diseases (VPD) common in childhood, the incidence of these viral infections has increased in the adult Japanese population [1]
Varicella and mumps were determined by enzyme immunoassay (EIA) and those to rubella were determined by hemagglutination inhibition (HI) assay
A high prevalence rate for the varicella antibody by EIA was observed in subjects of 2010 and 2011
Summary
Mumps, rubella, and varicella (MMRV) are vaccine-preventable diseases (VPD) common in childhood, the incidence of these viral infections has increased in the adult Japanese population [1]. The risk for death from measles or its complications is greater for infants, young children [2]. Since measles vaccine became available, professional and voluntary medical and public health organizations have collaborated in vaccination programs that have reduced the reported incidence of measles by greater than 99% [1]. Even countries that measles had been eradicated still have the high risk of importation from countries that have not yet eliminated the disease [3]. For prevention against MMRV infection in medical facilities, it is important to assess the immunity against these viruses and to achieve immunocompetence by vaccination
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