Abstract
Background: Sarcomatoid carcinoma is an uncommon malignancy, represents only 0.1% to 0.3% of carcinomas.
 Methods: The medical records of all the patients who underwent consecutive cystectomy and the TURBT specimen sent to pathology department of Sardar Patel Medical College, Bikaner, were retrospectively analysed. Detailed medical history was noted age, gender, indication for surgery, surgical procedure, tumour localization in the urinary bladder, diameter of the lesion after fixation with 10% formalin, and overall incidence of tumour reviewed in detail.
 Results: Out of the total 541 patients, 41 were found to have histological evidence of benign lesions of the urinary bladder, hence not included in the study. Out of 500 patients of urinary carcinoma 1 patient was found to have histological evidence of sarcomatoid carcinoma which was further confirmed by immunohistochemistry. The patient was 29 years old male. Gross haematuria was the clinical presentation. Radical cystectomy was performed. The tumour was polypoid, located on left posterolateral wall of the bladder with dimension of 10X7X6 cm.
 Conclusion: Sarcomatoid carcinoma is a rare variant with different therapeutic and diagnostic implications, presenting with gross haematuria. Sarcomatoid carcinoma was diagnosed on histological and immonohistological staining.
Highlights
Transitional cell carcinoma is the most prevalent bladder neoplasm
The term sarcomatoid carcinoma has been applied to this neoplasm, as the sarcomatoid features appear to be derived from dedifferentiation of the carcinomatous component.[7]
Out of these 541 patients, 41 patients were found to have histological evidence of benign conditions of bladder which were excluded from the study. 500 patients were diagnosed having urothelial carcinoma
Summary
Bladder cancer is a significant health problem with increasing incidence in parallel with the growing prevalence of tobacco smoking worldwide. It is the ninth most common cancer in the world and ranks second among all types of cancer in the urinary tract. Results: Out of the total 541 patients, 41 were found to have histological evidence of benign lesions of the urinary bladder, not included in the study. Out of 500 patients of urinary carcinoma 1 patient was found to have histological evidence of sarcomatoid carcinoma which was further confirmed by immunohistochemistry. Conclusion: Sarcomatoid carcinoma is a rare variant with different therapeutic and diagnostic implications, presenting with gross haematuria.
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