Abstract
Background: The genital infection due to Human papillomavirus (HPV) is considered as the most common sexually transmitted infection across the world, including high-risk oncogenic HPV (HR/HPV). Objective: This study aimed to determine the prevalence of HR/HPV genotypes among sexually active women in Parakou (Benin) in 2017. Methods: This research work was a cross-sectional descriptive study carried out in the city of Parakou (Benin), from January 15 to April 15, 2017. Sample consisted of 247 sexually active women selected through a systematic random sampling. Cervical specimens collected with swab were subject to multiplex PCR to characterize 14 HR/HPV genotypes. Results: The prevalence of HR/HPV infection was rated 32.8% [95% CI: 27.1-39.3]. All the fourteen HR/HPV genotypes investigated were detected using PCR among our study population. The most common types of HR/HPV were, in descending order, HPV45 (25.9%), HPV35 (18.5%), HPV52 (17.3%), HPV51 (16.0%) and HPV58 (14.8%). HPV16 and 18 were found out at respective proportions of 2.5% and 7.4%. Age group 20 years or less had the highest prevalence of HR/HPV infection (55.7%) followed by age group from 21 to 30 years (38.3%). Conclusion: The prevalence of HR/HPV infection is high among sexually active women in Parakou in 2017 and the most frequent HR/HPV are not those found commonly in precancerous and cancerous cervical lesions.
Highlights
Human papillomavirus (HPV) infection is one of the most widespread sexually transmitted infections across the world; more than half the sexually active women get infected with it during their existence [1, 2]
Epidemiological studies and experimental data showed that there is viral clearance in the infection, the Journal of Gynecology and Obstetrics 2020; 8(4): 102-107 persistence of high-risk oncogenic HPV (HR/HPV) infection plays a critical role in the development of cancer, and most cervical cancers are associated with HR/HPV [5]
The age specific distribution showed that the highest prevalence of HR/HPV infection was observed in age group years or less followed by age group from to 30 years in our study
Summary
Human papillomavirus (HPV) infection is one of the most widespread sexually transmitted infections across the world; more than half the sexually active women get infected with it during their existence [1, 2]. The genital infection due to Human papillomavirus (HPV) is considered as the most common sexually transmitted infection across the world, including high-risk oncogenic HPV (HR/HPV). Objective: This study aimed to determine the prevalence of HR/HPV genotypes among sexually active women in Parakou (Benin) in 2017. Sample consisted of 247 sexually active women selected through a systematic random sampling. Conclusion: The prevalence of HR/HPV infection is high among sexually active women in Parakou in 2017 and the most frequent HR/HPV are not those found commonly in precancerous and cancerous cervical lesions
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