Abstract
Mastitis is one of the major and keen parameter for quality and quantity of milkproduction. The recent study was conducted to estimate the occurrence rate of mastitis in four differentseasons of the year and its therapeutic cure in Llivestock Experiment Station Nili Ravi Bhunikey. Forthis purpose, the total of 1188 milk samples were screened for mastitis through California MastitisTest. Out of total 1188 milk samples, the prevalence rate of mastitis was 9.7% (27/279) in winter, 14%(40/286) in spring , 7.2% (23/320) in summer and 6% (18/303) in autumn respectively. An overallprevalence rate of mastitis was 9 %( 108/1188).The screened positive samples were subjected toculture on culture media. Seven antibiotics were selected for the fortitude of antibiotic sensitivityagainst the cultured organisms. Antibiotics used in current research were Gentamicin, Enrofloxacin,Amoxycillin, Norfloxacin, Tylosin, Oxytetracycline and Chloramphenicol. The efficacy of thedifferent antibiotics was checked by the configuration of the zone of inhibition. The outcome showedthat the incidence of mastitis was greater in spring and lower in autumn. From selected antibiotics,Enrofloxacin and Gentamycine have resulted in more effective against the cultured organism.
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