Prevalence of hepatitis C in patients with renal disease undergoing hemodialysis treatment

Marcos Frank Bastiani,Sandrine Comparsi Wagner,Graziella Gasparotto Baiocco

doi:10.5935/1676-2444.20140035

Marcos Frank Bastiani, Sandrine Comparsi Wagner + Show 1 more

Open Access

https://doi.org/10.5935/1676-2444.20140035

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Abstract

Introduction and Objective: This study aimed at determining the prevalence of hepatitis C among 649 patients diagnosed with chronic or acute kidney disease − patients were undergoing hemodialysis treatment at a large hemodialysis center in Porto Alegre-RS, from January through December, 2012 –, as well as relating our data to that presented in the national census, reporting cases of coinfection by hepatitis C and human immunodeficiency virus (HIV), and defining the demographic profile of these patients. Method: An observational cross-sectional study was conducted and data was obtained from information in patients’ electronic medical records. Result and conclusion: The prevalence of hepatitis C in this study was 10.17% of the sampled population. However, further analysis of other liver centers would be required to estimate an accurate prevalence rate of infection caused by the hepatitis C virus in patients undergoing hemodialysis in Porto Alegre.

Highlights

Introduction and objectiveThis study aimed at determining the prevalence of hepatitis C among 649 patients diagnosed with chronic or acute kidney disease − patients were undergoing hemodialysis treatment at a large hemodialysis center in Porto Alegre-Rio Grande do Sul (RS), from January through December, 2012, as well as relating our data to that presented in the national census, reporting cases of coinfection by hepatitis C and human immunodeficiency virus (HIV), and defining the demographic profile of these patients
The prevalence of hepatitis C observed in the present study (10.17%) may be considered low when compared to the survey by Gomes et al (2006), which reported 29.1% of hepatitis C virus (HCV) infection in dialysis patients in Porto Alegre-RS
It is very similar to the study by Leão et al (2007), in which 10.7% were described in Juiz de Fora-MG[9, 13]

Summary

Introduction

Renal disease is defined by damaged or decreased kidney function. Renal damage can result from any disease potentially able to reduce the functional capacity of the kidneys. Renal patients that undergo hemodialysis are prone to contamination by HCV due to the several risk factors they are exposed to. Among these factors, we may draw attention to treatment duration, blood transfusions and the virus prevalence in the hemodialysis unit[12, 13]. According to Boletim Epidemiológico de Hepatites Virais de 2012, from 1999 to 2011, in the South region, 18,307 confirmed cases of hepatitis C were reported to the Notifiable Diseases Information System (SINAN) This represents 22.3% of the notified cases in Brazil. Prevalence of hepatitis C in patients with renal disease undergoing hemodialysis treatment

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