PREVALENCE OF HEPATITIS B VIRUS INFECTION AMONG HIV PATIENTS INBENUE SOUTH SENATORIAL DISTRICT, NIGERIA

Abstract

Hepatitis B infection seriously threatens global public health, especially in developing nations. Despite severalefforts on ascertaining the true prevalence of HBV, it tenaciously varies across different locations and subpopulations, particularly among those at risk of infection such as the HIV-infected population. This study aimed atdetermining the sero-prevalence of HIV-HBV co-infection in Benue South Senatorial District, Nigeria. This crosssectional study was conducted in four anti-retroviral therapy (ART) specialized clinics between May 1, andSeptember 2023 using pretested questionnaires, after obtained ethical approval and informed consent.Bloodsamples of participants were screened using HBsAg testing kitsand the results were interpreted according to themanufacturer’s instructions. The screening for HIV-HBV co-infection showed a sero-prevalence of 25/457 (5.47%).The distribution based on clinic location was 12(48%) GH Otukpo, 8(32%) GH Oju, 2(8%) GH Ugbokpo and3(12%) SMH Okpoga. The distribution also revealed that most cases were in the age group 40-49 and the femalegender.The prevalence showed that only 3/25 (12.0%) reported a history of sexually transmitted diseases other thanHIV while 2/25 (8.0%) had a history of multiple sex partners. Most co-infected cases 23/25(92.0%) had no historyof same-sex relationships and 23/25(92.0%) had recent history of unprotected sex. In Nigeria, hepatitis B infectionremains a significant public health problem. Notable preventive strategies include abstinence from sex, avoidanceof multiple sex partners, strict adherence to safe sex, and avoiding contact with infected body fluids. Otherstrategies such as averting mother-to-infant hepatitis B transmission, scale-up of screening programs and extensivevaccination programs are eminently recommended in the course of HBV control.