Abstract
Introduction: To investigate the prevalence of enteroaggregative Escherichia coli (EAEC) in children 0.05). Conclusion: The present study revealed the high prevalence of EAEC in children with diarrhea in this region that should be more considered in preventing, diagnosis and treatment strategies. We conclude that using multiple virulence genes simultaneously for detection of this strain is necessary to gain reliable results with pointing to aspU as preferred gene for detecting EAEC when diagnosis based on the presence of one virulence marker. To the best of our knowledge, this is the first report on the prevalence of EAEC strains in the northwest of Iran.
Highlights
To investigate the prevalence of enteroaggregative Escherichia coli (EAEC) in children < 10 years with a diagnosis of gastroenteritis by multiplex polymerase chain reaction (MPCR)
A total of 303 diarrheal stool samples from patients admitted to Tabriz children s hospital with diagnosis of gastroenteritis were enrolled in cross-sectional study for detection of three virulence genes using MPCR
The present study revealed the high prevalence of EAEC in children with diarrhea in this region that should be more considered in preventing, diagnosis and treatment strategies
Summary
To investigate the prevalence of enteroaggregative Escherichia coli (EAEC) in children < 10 years with a diagnosis of gastroenteritis by multiplex polymerase chain reaction (MPCR). A total of 303 diarrheal stool samples from patients admitted to Tabriz children s hospital (the referral center in East Azerbaijan province of Iran) with diagnosis of gastroenteritis were enrolled in cross-sectional study for detection of three virulence genes using MPCR.
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