Prevalence of Congenital Anomalies in Polyhydramnios: A hospital based study from Western Nepal

Prakash Sharma,Sangeeta Devi Gurung,Subita Lalchan

doi:10.3126/njr.v8i1.20452

Prakash Sharma, Sangeeta Devi Gurung + Show 1 more

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https://doi.org/10.3126/njr.v8i1.20452

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Abstract

Introduction: Polyhydramnios is excessive amount of amniotic fluid in relation to gestational age. It is frequently associated with congenital anomalies of the fetus. The aim of this study was to see the prevalence of congenital anomalies in polyhydramnios.Methods: Singleton pregnant irrespective of gestational age with amniotic fluid index more than 25 were included in the study. Degree of polyhydramnios was graded as mild, moderate and severe. Detail study of fetus was done for possible congenital anomalies. Congenital anomalies were confirmed with post-natal findings.Results: There were 39 pregnant women with amniotic fluid index (AFI) > 25 cm. Prevalence of polyhydramnios was 0.3%. Congenital anomalies were present in 31.6 % of pregnant women with polyhydramnios. In pregnant women with severe polyhydramnios; 66.6 % had congenital anomalies. Central nervous system, gastrointestinal and skeletal anomalies were the frequent anomalies associated with polyhydramnios.Conclusion: Polyhydramnios is associated with increased risk of congenital anomalies hence a detail survey of fetus should be done for possible congenital anomalies.

Highlights

Polyhydramnios is excessive amount of amniotic fluid in relation to gestational age
One of the pregnant lady with history of cardiac disease was excluded from the study
A total of 38 pregnant ladies with polyhydramnios were included for statistical analysis

Summary

Introduction

Polyhydramnios is excessive amount of amniotic fluid in relation to gestational age. It is frequently associated with congenital anomalies of the fetus. Lalchan S et al Polyhydramnios and Congenital Malformations between the placenta and the fetal blood and transudation of water and electrolytes across the amnion and chorion; movement of water across fetal skin and fetal swallowing are the sources influencing amniotic fluid volume.[1] Polyhydramnios is the excess of the amniotic fluid relative to the gestational age. It occurs in 1% of pregnancies.[2] It may be associated with adverse fetal and maternal outcome. To the best of our knowledge, no such study has been done in our part

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