Prevalence of Chronic Kidney Disease in Patients With or at a High Risk of Cardiovascular Disease

Abstract

This secondary analysis of data from the MULTIRISC study investigated the prevalence of chronic kidney disease (CKD) in patients who either had or were at a high risk of cardiovascular disease. The original, epidemiological, cross-sectional, multicenter study was carried out in outpatient clinics belonging to cardiology, internal medicine and endocrinology departments. It included patients aged > or = 18 years with a high cardiovascular risk (i.e., a SCORE [Systematic Coronary Risk Evaluation] risk >5% or diabetes mellitus or associated clinical disease). The definition of CKD was an estimated glomerular filtration rate (Modification of Diet in Renal Disease formula) <60 mL/min per 1.73 m2. Established CKD was regarded as present when, in addition, the serum creatinine level was > or = 1.3 mg/dL in men or > or = 1.2 mg/dL in women, and occult CKD as present when the creatinine level was lower. In total, 2608 patients were included. Some 62.7% did not have CKD, 18.9% had established CKD and 18.4% had occult CKD. In summary, CKD was highly prevalent in patients with a high risk of cardiovascular disease.