PREVALENCE MORNING HYPERTENSION IN TREATED PATIENTS OLDER THAN 55 YEARS: PP.37.500

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Analysis of the prevalence of morning hypertension (MH) is usually conducted with the use of mean home systolic blood pressure (MSBP) and morning-evening difference (M-ED) variables. Since there is currently no consensus on the level of M-ED values, information on the prevalence of MH is limited. Objective: The aim was to determine the optimal M-ED value and assess the prevalence of MH by using home blood pressure measurements (HBPM) in treated pts in Moscow population. Methods: In our study 1876 residents of Moscow over 55 ages were randomly selected from long observed cohort (mean age 68.9[8], 43% males). HBPM was performed during 4 days in the morning/evening, before medication intake. The automatic device A&D-668B and standard arm cuff were used. Stepwise logistic regression was performed to test 8 variables in order to select the M-ED values>10, >15 or >20mmHg. The analysis model was used age- and sex- adjusted. MH was defined as MSBP>135mmHg and M-ED>selected value. To summarize the data, the analysis of 2x2 contingency tables was done with corresponding statistics: Wald xi-square and contingency coefficient Phi. Pts without MH were classified as controlled BP (C) pts. Pts with MH were classified as uncontrolled BP treated (UnT) pts. Pts with MSBP <135 mmHg and dominated morning SBP were determined as C/+(M-ED) pts. Pts with MSBP >135 mmHg without dominated morning SBP were determined as UnT/-(M-ED) pts. Results: Data of 782 treated pts were analyzed (mean age 69[6], males 44%). M-ED>15mmHg (p = 0,002) was evaluated as optimal value in comparison with >10mmHg(p = 0,01) and >20 mmHg (p = 0,14). Cpts were 36%. C/+(M-ED) were 1%. UnT were 10%. UnT/-(M-ED) were 53%. Conclusion: In a sample of the Moscow population the prevalence of morning hypertension in treated patients >55 was 10%, according to morning-evening difference >15 mmHg, selected as the optimal diagnostic value.