Abstract
Hepatitis G virus (HGV) is a recently described hepatotropic parenterally transmitted flavivirus. The presence of HGV was tested in 61 patients with a request for confirmation of HCV active infection. Thirty-two patients were in haemodialysis and 29 were referred from wards other than nephrology. Active HCV and HGV infections were determined by detection of their viral RNA in serum. Evaluation of previous HGV infection was carried out by detection of antibodies to E2 antigen. HCV prevalence was 62.29% (38/61). HGV-active infection was found in 11.47% (7/61) of the population studied: in 18.7% (6/32) of the haemodialysed patients and in 3.4% (1/29) of patients belonging to the other group. HGV prevalence increased two-fold when previous infection was also considered. HGV clearance was prospectively detected in 5 out of the 7 patients with active infection, and at an earlier stage for those patients coinfected with HCV. Anti-E2 seropositivity was associated with HGV clearance in only two patients.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.