Abstract

Background and Aims: Coronary artery disease (CAD) constitute a major cause of cardiovascular morbidity and mortality worldwide with an enormous burden on healthcare resources. Prevalence and pattern of CAD in patients of rheumatic and non-rhemuatic valvular heart diseases varies widely with limited data on optimal strategies for diagnosis and treatment.Methods: This study includes 97 patients with rheumatic and non-rheumatic valvular heart disease who underwent coronary angiogram (CAG) before cardiac surgery. Patients were divided into two groups based on rheumatic heart disease (RHD) & non-rheumatic disease (Non-RHD) and correlate the patterns of CAD.Results: Out of 97 patients, 22 (22.6%) patients were found to have significant CAD. In patients with non-rheumatic origin CAD was common (15 patients, 68.1%) as compared to rheumatic origin (7 patients, 31. 8%). In rheumatic origin, the prevalence was 7(12.2%) out of 57 patients while in non-rheumatic origin, was 15(37.5%) out of 40 patients. In RHD group, all patients with CAD were found to have single vessel diease (SVD) while, in non-RHD group, 11 patients (73.3%) had SVD, 3 patients (16.7%) had double vessel disease (DVD) and one patient (5.6%) had triple vessel disease (TVD).Conclusions: Prevalence of CAD is higher in patients with non-RHD in comparison to those with RHD. We also found SVD to be the most common pattern of CAD in both rheumatic and non-rheumatic valvular heart disease.

Highlights

  • Rheumatic heart disease (RHD) continues to be the dominant form of valvular heart disease in developing nations[1]

  • Here we evaluate the prevalence of coexistent coronary artery disease and its risk factors in patients who underwent valve surgery for rheumatic and non-rheumatic valvular heart disease in last one year at Manmohan Cardio Vascular Thoracic and Transplant Centre (MCVTC)

  • A total of 97 patients with valvular heart diseases were included in the study

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Summary

Introduction

Rheumatic heart disease (RHD) continues to be the dominant form of valvular heart disease in developing nations[1]. There are limited data regarding optimal strategies for diagnosis and treatment of coronary artery disease (CAD) in patients with valvular and non valvular heart disease having concomitant CAD. The strategies for diagnosis of CAD were followed from the smaller published series of patients who underwent surgical treatment for valvular heart disease (VHD). Coronary artery disease (CAD) constitute a major cause of cardiovascular morbidity and mortality worldwide with an enormous burden on healthcare resources. Prevalence and pattern of CAD in patients of rheumatic and non-rhemuatic valvular heart diseases varies widely with limited data on optimal strategies for diagnosis and treatment

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