Abstract
Introduction: Staphylococci form the commonest agent of hospital infections and pose a major problem because of their growing resistance to the commonly used treatments. Aim: The aim of this study is to survey for the prevalence of antibiotic susceptibility pattern of Staphylococcus aureus strains from clinical samples to common antibiotics in Minna, Nigeria. Method: All samples from wound swab, stool, blood, urine, urethra, endocervical swab, eye, ear, breast abscess etc submitted to General hospital Minna were cultured on sterile blood agar and mannitol salt agar and incubated at 37oC for 24hrs using standard microbiological techniques. Results: Of the 323 different specimens, (79.26%) S.aureus isolates were reported. The highest carrier rate of S. aureus (90.91%) occurred in wound while the least (72.01%) was reported in others. The isolates were highly susceptible to fusidic acid (26.41%) oxacilin (24.32%) vancomycin (20.75%) and trimethoprim (18.86%). Conclusion: fusidic acid with relatively higher susceptibility to clinical isolates of S.aureus can be used for management of these clinical conditions in our locality. The need for appropriate health education to reduce self medication and drug abuse is very imperative and desirous
Highlights
Staphylococci form the commonest agent of hospital infections and pose a major problem because of their growing resistance to the commonly used treatments
The overall prevalent rate of 78.26% observed among the clinical isolate is comparatively higher than the report of Onanuga et al[12] who document a 36% isolates
Obiazi et al 10 reported a much higher carrier rate of (20.8%). This Pattern of prevalence may be related to the level of S. aureus infection in our locality
Summary
Staphylococci form the commonest agent of hospital infections and pose a major problem because of their growing resistance to the commonly used treatments. Aim: The aim of this study is to survey for the prevalence of antibiotic susceptibility pattern of Staphylococcus aureus strains from clinical samples to common antibiotics in Minna, Nigeria. Results: Of the 323 different specimens, (79.26%) S.aureus isolates were reported. The highest carrier rate of S. aureus (90.91%) occurred in wound while the least (72.01%) was reported in others. Conclusion: fusidic acid with relatively higher susceptibility to clinical isolates of S.aureus can be used for management of these clinical conditions in our locality. 2-3% of the population have chronic furunculosis.[1] Staphylococcus aureus has associated with different clinical conditions. It is still one of the most frequently encountered single bacterial species in www.ijbar.ssjournals.com
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