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Abstract
The interstitial fluid pressure-volume relationship was studied in patients who developed leg edema following arterial reconstruction for femoropopliteal atherosclerosis. The increase in subcutaneous tissue volume of the operated limbs was estimated by surface measurements and computed tomography. The subcutaneous interstitial fluid pressure ( P if) of the legs was recorded by the wick-in-needle technique and averaged −0.7 mm Hg in healthy controls. Postoperatively, P if was −0.8 mm Hg in patients who did not develop local edema compared to +2.2 mm Hg in patients with postoperative edema. if increased with increasing subcutaneous tissue volume in patients with moderate edema (0–100% subcutaneous tissue volume increase), but insignificant further increase in P if was observed with additional edema (100 to 600%). A maximal P if of +5 mm Hg was observed in edematous legs indicating a high compliance of the subcutaneous tissue in patients with postreconstructive leg edema.
Published Version
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